《Slide 76.》Adenomyosis, Uterine corpus

A. Brief Descriptions：

1. Definition: ectopic islands of endometrial tissue in the myometrium.

2. Symptoms: menorrhagia or dysmenorrhea; general and not diagnostic.

B. Gross Findings：

1. Uterine enlargement & irregular thickening of the uterine wall, with red-brown blood pigmentation within the myometrium in some cases.

C. Micro Findings：

1. Ectopic nests of endometrial glands enclosed within a spindle cell stroma between the muscle bundles of the myometrium.

2. The nests should be one low power field or more (2 to 3 mm) below the endomyometrial junction.

D. Others:

1. DDx:

   Ectopic endometrial tissue in the myometrium of uterus: adenomyosis.

   Ectopic endometrial tissue in abnormal location outside the uterus: endometrisis.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  P.1057.

　

　

 

【 Fig. 76-1 (LP)】Several ectopic islands of endometrial tissue embedded in the myometrium.

　

 

 

【 Fig. 76-2 (LP)】Islands of endometrial tissue and myometrium.

　

 

 

【 Fig. 76-3 (HP)】Endometrial tissue includes endometrial glands and endometrial stroma in this section.