Slide 129.Hydronephrosis, Kidney

A. Brief Descriptions

  1. Hydronephrosis is the term used to describe dilation of the renal pelvis and calyces associated with progressive atrophy of the kidney due to obstruction to the outflow of urine.

B. Gross Findings

  1. Obstructive uropathy; form a continuous spectrum from minor changes of blunting of the renal papillae to severe from where kidney converted into a multiseptate sac with paper-thin walls.

C. Micro Findings

  1. Thinning renal parenchyma with residual large renal vessels in the hilum; note dilated renal pelvis with flattened epithelia.

  2. Sclerosis of glomeruli with atrophic tubules; note renal pelvis with flattened epithelia.

D. Others:

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E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  p.988

 

 

 

Fig. 129-1 (1X)Thinning renal parenchyma with residual large renal vessels in the hilum; note dilated renal pelvis with flattened epithelia.

 

 

 

Fig. 129-2 (2X)Sclerosis of glomeruli with atrophic tubules.

 

 

 

Fig. 129-3 (2X)Atrophic tubules with chronic inflammatory infiltrate in interstitium.

 

 

 

Fig. 129-4 (10X)Renal pelvis with flattened epithelia.