《Slide 148.》Molluscum contagiosum, Skin
A. Brief Descriptions：
Common, self-limited viral disease of the skin caused by a poxvirus.
Multiple lesions with a predilection for the truck and anogenital area.
Firm, puritic, pink to skin-colored umbilicated papules.
B. Gross Findings：
Waxy pink or skin-colored, firm, prutic papules with umbilicated center
C. Micro Findings：
Epithelial hyperplasia with epidermal growth downward in lobules.
Many epidermal cells contain large intracytoplasmic inclusion bodies, the so-called molluscum bodies.
The molluscum bodies grow in size as they move toward the surface.
In the horny layer, numerous large, basophilic molluscum bodies lie enmeshed in a network of eosinophilic horny fibers.
In the center of the lesion, the stratum corneum ultimately disintegrates, releasing the molluscum bodies and forming a central crater.
The surrounding dermis shows little or no inflammatory reaction.
1. Viral disease of the skin (Poxvirus)
2. Age: children & young adults; esp. males
3. Predilection site: trunk and anogenital areas
【 Fig. 148-1 (4X)】
【 Fig. 148-2 (10X)】
【 Fig. 148-3 (20X)】