A. Brief Descriptions：
One of the most common soft tissue sarcoma of adulthood.
2. A peak incidence between 40 and 60 years,
with two major sites in the extremities (thigh) and the
B. Gross Findings：
Tend to be well circumscribed or encapsulated with a lobulated pattern and satellite nodules.
C. Micro Findings：
Five basic histological categories:
Round cell liposarcoma.
Well-differentiated liposarcoma (including atypical lipoma).
In our slide:
An extreme degree of cellular pleomorphism with different differentiated stages of lipoblasts and some bizarre multinucleated tumor giant cells.
Lipoblast: hyperchromatic, scalloped nuclei with prominent nucleoli and different content of intracellular lipid material.
Mitosis is easily seen.
Areas of myxoid change are also noticed.
Robbins Pathologic Basis of Disease, 6th ed. P1261.
【 Fig. 150-1 (LP)】 Hypercellular tumor with focal myxoid change (center).
【 Fig. 150-2 (LP)】
【 Fig. 150-3 (LP)】 Extreme degree of cellular pleomorphism with different differentiated stages of lipoblasts.
【 Fig. 150-4 (HP)】 Lipoblasts with hyperchromatic, scalloped nuclei which were pushed by intracytoplasmic fatty vacuoles.