《Slide 7.》Fatty liver, Liver
A. Brief Descriptions：
Cause: alcoholic , obesity , non-alcoholic steatohepatitis….
Abnormal accumulation of neutral triglyceride (fat) in hepatocytes , when severe may impair cellular function.
B. Gross Findings：
Mild fatty change: no gross change.
Progressive change: enlarges and getting yellow.
Severe: enlarge，pale or bright yellow，soft，greasy and may even weigh 3~6 kg.
C. Micro Findings：
Many small globular intracytoplasmic clear space, may accumulate and displace the nucleus to the periphery.
Contiguous cells may rupture to produce fatty cyst.
Fat vacuoles in the cytoplasm around the nucleus.
特殊染色: prepare by frozen section and stained by Sudan III or Sudan black.
Robbins Pathologic Basis of Disease, 6th ed. P.39-40.
【 Fig. 7-1 (LP)】
【 Fig. 7-2 (LP)】
【 Fig. 7-3 (HP)】.
【 Fig. 7-4 (HP)】
【 Fig. 7-5 (HP)】.