Slide 26.Heart failure cell, Lung

A. Brief Descriptions

  1. Left ventricle fail to keep pace with the venous return from the lungs, pulmonary congestion and edema results.

  2. Intra-alveolar precipitate and widening of alveolar septa at first.

  3. Heart failure cell: hemosiderin laden macrophage in lung.

  4. Long persistence septal edema often induces fibrosis within the alveolar wall.

B. Gross Findings


C. Micro Findings

  1. Heart failure cell presented in alveolar spaces.

  2. Congestion and hemorrhage.

  3. Anthracotic deposits in alveolar septi.

D. Others:


E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  P.549.




Fig. 26-1 (LP)The alveolar spaces are filled with exudate and brownish heart failure cells; note entrapped air bubbles and thickened alveolar septi.



Fig. 26-2 (HP)Heart failure cells as hemosiderin laden macrophages in the alveolar spaces; note anthracosis (dark brown carbon dusts) of the interstitium (right upper).