Slide 25.Splenic infarction, Spleen

A. Brief Descriptions

  1. Nearly 99% of infarcts are caused by thromboembolic events, and almost all are the result of arterial occlusions.

  2. White infarcts are encountered with arterial occlusion and in solid tissues.

B. Gross Findings

  1. Recent infarcts are hemorrhagic,whereas older, more fibrotic infarcts are pale yellow-gray.

C. Micro Findings

  1. Necrotic area with homogenous pinkish appearance.

  2. Hematoidin crystals can be found in this section.

  3. Inflammatory cells seated on the margin of infarct area.

D. Others:


E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  P.689-690.




Fig. 25-1 (LP)Splenic infarction (left) with homogenous pinkish appearance.




Fig. 25-2 (LP)Inflammatory cells seated on the margin of infarct area.




Fig. 25-3 (LP)Inflammatory cells.




Fig. 25-4 (HP)Hemosiderin laden macrophages in the more fibrous areas (junction of infarction ).