《Slide 17.》Acute suppurative appendicitis, Appendix

A. Brief Descriptions：

1. Cause : It is associated with obstruction (fecalith, gallstone, tumor or ball of worms).

2. Abscess formation within the wall and foci of suppurative necrosis in the mucosa.

B. Gross Findings：

1. Congested & swollen.

2. Dilated lumen contain pus, or a fecalith, or both.

3. Serosa coated with fibrin, fibrinopurulent exudate, or pus.

C. Micro Findings：

1. Mucosal ulceration & infiltration by PMNs, eosinophils, plasma cells, &lymphocytes throughout all layers & frequently into serosa.

2. More advanced stage, the inflammatory process involved the full thickness of wall,with partial necrosis or infarction of wall (perforated areas).

D. Others:

1. Classified into acute, suppurative, & gangrenous stages.

    

   site	acute	suppurative	gangrenous
   mucosa	neutrophils	suppurative necrosis	hemorrhagic ulceration
   wall	neutrophils	suppurative necrosis	green-black necrosis
   serosa	congested blood vessels fibrinous exudates	purulent exudates	green-black necrosis

    

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  P.839-840.

　

 

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