《Slide 186.》Mature cystic teratoma, Ovary
A. Brief Descriptions:
Teratoma: true neoplasm derived from totipotential cells and composed of a variety of parenchymal cell types representative of more than one germ layer, usually all three.
Mature teratoma: teratoma composed of mature elements indistinguishable with normal tissue; benign and cystic.
B. Gross Findings:
Uniloculated or multiloculated cystic cavities filled with fatty or sebaceous material and hair → ”dermoid cyst”.
C. Micro Findings:
Ectoderm: The cystic lesion is lined by skin with its sebaceous glands and hair follicles.
Mesoderm: fibrous and fatty tissue.
Endoderm: thyroid tissue with thyroid follicles of various sizes.
Compare with dermoid cyst,ovary (slide 38) and teratoma,tesis (slide 39).
Robbins Pathologic Basis of Disease, 6th ed. P.1073-1074.
【 Fig. 186-1 (LP)】Mature skin with sebaceous glands and hair follicles.
【 Fig. 186-2 (LP)】Mature sweat glands and adipose tissue.
【 Fig. 186-3 (LP)】Mature hair follicles, adipose tissue and vessels.
【 Fig. 186-4 (LP)】Mature thyroid follicles.