《Slide 84.》Fibroadenoma, Breast

A. Brief Descriptions：

1. Most common benign tumor of the female breast.

2. Frequently multiple and bilateral and occur in the upper outer quadrant.

3. A  new growth compose of both fibrous and glandular tissue.

B. Gross Findings：

1.    Grow as a spherical nodule which is usually well-circumscribed and freely movable.

2.    Vary in size from less than 1 cm to giant forms 10 to 15 cm in diameter.

C. Micro Findings:

1. A well circumscribed nodule with fibrous capsule.

2. Proliferation of both duct and periductal connective tissue.

3. Connective tissue: fibromyxomatous stroma

4. Duct: 2 growth pattern:

• Pericanalicular pattern: round or oval duct.

• Intracanalicular pattern: slit-like duct.

D. Others:

 1.Compare with slide 85, phyllodes timor of breast.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  P.1102-1103.

　

 

 

【 Fig. 84-1 (LP)】Multiple fibroadenoma with fibrous capsule.

　

　

 

【 Fig. 84-2 (LP)】Proliferation of both duct and periductal fibromyxomatous stroma.Note the intracanalicular pattern of slit-like duct.

 

 

【 Fig. 84-3 (LP)】Pericanalicular pattern: the duct with round or oval duct.