《Slide 88.》Mucinous carcinoma, Breast

A. Brief Descriptions：

  1. Colloid carcinoma.

  2. Invasive carcinoma of breast; tends to occur in older women and grows slowly; pure form with an excellent short-term prognosis.

B. Gross Findings：

  1. Well circumscribed and formed by a currant jelly-like mass held together by delicate septa.

  2. Cystic degeneration has been reported in relatively large tumrs.

C. Micro Findings：

  1. Extracellular mucin pooling that dissect and extend into the contiguous tissue spaces and planes of cleavage.

  2. Small islands and isolated neoplastic cells are floating within a sea of mucin.

D. Others:

  1. Compare with slide 88, infiltrating ductal carcinoma of breast.

E. Reference：

  1. Robbins Pathologic Basis of Disease, 6th ed.  P.1112.

 

 

【 Fig. 88-1 (LP)】Lakes of slightly staining mucin with island of neoplastic cells floating.

　

 

 

【 Fig. 88-2 (LP)】The neoplastic cells arrange in nests.

　

 

 

【 Fig. 88-3 (LP)】Some tumor cells form cribriform or glandular pattern.

　

 

 

【 Fig. 88-4 (HP)】Tumor cells have hyperchromatic nuclei and some have distinct nucleoli.