Slide 127.Chronic glomerulonephritis, Kidney

A. Brief Descriptions

  1. Chronic glomerulonephritis is best considered an end-stage pool of glomerular disease fed by a number of streams of specific types of glomerulonephritis

  2. Poststreptococcal GN, rapidly progressive GN, membranous GN, focal glomerulosclerosis, membranoproliferative GN, …etc. à chronic GN.

B. Gross Findings

  1. Small, firm kidney with granular subcapsular surface & narrowed cortex.

C. Micro Findings

  1. Changes varying greatly, the following may be found:

D. Others:


E. Reference:

  1. Robbins Pathologic Basis of Disease, 6th ed.  p.963-964




Fig. 127-1 (4X)Small, solid tuft, some with cellular proliferation and adhesion of tuft and capsule.




Fig. 127-2 (10X)Glomerulus undergoes sclerosis.




Fig. 127-3 (4X)Glomerulosclerosis seen in left lower field and tubular atrophy with chronic inflammatory infiltrate.



Fig. 127-4 (4X)Atrophic renal tubules with chronic inflammatory infiltrate and hemorrhage in fibrous stroma.