《Slide 127.》Chronic glomerulonephritis, Kidney
A. Brief Descriptions：
Chronic glomerulonephritis is best considered an end-stage pool of glomerular disease fed by a number of streams of specific types of glomerulonephritis
Poststreptococcal GN, rapidly progressive GN, membranous GN, focal glomerulosclerosis, membranoproliferative GN, …etc. à chronic GN.
B. Gross Findings：
Small, firm kidney with granular subcapsular surface & narrowed cortex.
C. Micro Findings：
Changes varying greatly, the following may be found:
Small, solid tuft, some with cellular proliferation & adhesion of tuft & capsule, or crescent formation.
Loss, atrophy, or dilatation, some with infection.
Robbins Pathologic Basis of Disease, 6th ed. p.963-964
【 Fig. 127-1 (4X)】Small, solid tuft, some with cellular proliferation and adhesion of tuft and capsule.
【 Fig. 127-2 (10X)】Glomerulus undergoes sclerosis.
【 Fig. 127-3 (4X)】Glomerulosclerosis seen in left lower field and tubular atrophy with chronic inflammatory infiltrate.
【 Fig. 127-4 (4X)】Atrophic renal tubules with chronic inflammatory infiltrate and hemorrhage in fibrous stroma.