《Slide 134.》Wilms' tumor, Kidney

A. Brief Descriptions：

1. Wilms’ tumor is also known as nephroblastoma, embryoma, carcinosarcoma, adenosarcoma, and adenomyosarcoma.

2. It is seen primarily in infants, 50% of the cases occurring before the age of 3 years and 90% before the age of 6 years.

B. Gross Findings：

1. Large，solitary，well-circumscribed mass

2. Tan to gray、soft 、homogeneous on cut surface

C. Micro Findings：

1. Classic triphasic components:

• Blastemal.

• Stromal.

• Epithelial cell type.

D. Others:

1. 10% are bilateral or multiple.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  p.487-489

　

 

 

【 Fig. 134-1 (2X)】Relatively solitary well-circumscribed mass.The most are Blastemal type.

　

 

【 Fig. 134-2 (10X)】Most are oval to round hyperchromatic cancer cells with  scanty cytoplasm.The lesion is Blastemal type.

　

 

【 Fig. 134-3 (10X)】Some area shows more spindle cells type with eosinophilic stroma indicating stromal differentiation.

　

 

【 Fig. 134-4 (10X)】Focal glandular formation is seen in this view indicating toward epithelial differention.