《Slide 134.》Wilms' tumor, Kidney
A. Brief Descriptions：
Wilms’ tumor is also known as nephroblastoma, embryoma, carcinosarcoma, adenosarcoma, and adenomyosarcoma.
It is seen primarily in infants, 50% of the cases occurring before the age of 3 years and 90% before the age of 6 years.
B. Gross Findings：
Tan to gray、soft 、homogeneous on cut surface
C. Micro Findings：
Classic triphasic components:
Epithelial cell type.
10% are bilateral or multiple.
Robbins Pathologic Basis of Disease, 6th ed. p.487-489
【 Fig. 134-1 (2X)】Relatively solitary well-circumscribed mass.The most are Blastemal type.
【 Fig. 134-2 (10X)】Most are oval to round hyperchromatic cancer cells with scanty cytoplasm.The lesion is Blastemal type.
【 Fig. 134-3 (10X)】Some area shows more spindle cells type with eosinophilic stroma indicating stromal differentiation.
【 Fig. 134-4 (10X)】Focal glandular formation is seen in this view indicating toward epithelial differention.