Slide 182.Psoriasis vulgaris, Skin

A. Brief Descriptions

  1. Common chronic inflammatory dermatosis.

  2. Elbow, knees, scalp, lumbosacral area, intergluteal cleft, glans penis.

  3. Well-demarcated, pink to salmon-colored plaque covered by loosely adherent  scales.(Auspitz sign) 

B. Gross Findings

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C. Micro Findings

  1. Epidermal hyperplasia with elongation of the rete ridge.

  2. Stratum granulosum: thinned or absent with dilated, tortuous blood vessels within these papillae.

  3. Parakeratotic scales with microabscess of neutrophils within the superficial epidermal layer. (Munro microabscess) .

D. Others

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E. Reference

  1. Robbins pathologic basis of disease. Ch27. p.1199.

 

Fig. 182-1 (4X)

 

 

 

Fig. 182-2 (10X)

 

 

 

Fig. 182-3 (20X)

 

 

 

Fig. 182-4 (20X)

 

 

 

Fig. 182-5 (20X)

 

 

 

Fig. 182-6 (40X)