Slide 156.Avascular necrosis, Femur

A. Brief Descriptions

  1. Also called osteonecrosis.

  2. Infarction of bone and marrow.

  3. Caused by interruption of blood flow induced by a mechanical disruption, such as fracture, dislocation, or thrombosis.

B. Gross Findings


C. Micro Findings

  1. Necrotic bone.

  2. Sclerotic bone.

  3. Calcification.

  4. Vascular granulation tissue.

D. Others:

  1. What is different between avascular necrosis and osteomyelitis?

E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  P1231.



Fig. 156-1 (LP)