《Slide 11.》Malaria pigment (Hemozoin), Liver

A. Brief Descriptions：

1. Malaria caused by the intracellular protozoan parasite. ( Plasmodium falciparum…).

2. Malaria pigment formed by the break-down of hemoglobin of RBC.

3. It is brown-black pigment and yellow-orange in polarized light.

B. Gross Findings：

1. Enlarged, congested, dark red to slate gray.

C. Micro Findings：

1. Congested sinusoids, & some disarrangement of hepatic cords.

2. Hypertrophy Kupffer cells containing parasitized or unparasitized RBC, remnants of parasites, hemozoin granules, & occasional hemosiderin.

D. Others:

1. 病理組織重點: Hypertrophy Kupffer cells containing parasitized or unparasitized RBC, remnants of parasites, hemozoin granules, & occasional hemosiderin.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  P.390-391.

　

 

 

【 Fig. 11-1 (LP)】

　

 

 

【 Fig. 11-2 (LP)】

　

 

 

【 Fig. 11-3 (LP)】

　

 

 

【 Fig. 11-4 (HP)】