《Slide 38.》Dermoid cyst, Ovary

A. Brief Descriptions：

  1. Benign cystic teratoma (dermoid cyst) is the most common ovarian neoplasm , comprising up to 25% or more of all ovarian tumors.

  2. Contain various mature tissues derived from one or more of the embryonic germ layers : the ectoderm, mesoderm, and endoderm.

B. Gross Findings：

  1. Cystic mass containing thick sebaceous material and hairs.

  2. The internal lining is smooth but frequently has a knob-like nodular protrusion in one.

  3. Area (the “umbo”), in which cartilage, bone, and well-formed teeth may be present.

C. Micro Findings：

  1. Skin element (dermal appendages, e.G. Hair follicles, sebaceous glands).

  2. Endodermal element (respiratory and gastrointestinal epithelia).

  3. Mesodermal element (muscle, fat, cartilage).

  4. Glial element.

D. Others:

  1. Account for 15% of ovarian neoplasm, 10% bilateral.

E. Reference：

  1. Robbins Pathologic Basis of Disease, 6th ed.  P.1073-1075.

　

 

 

【 Fig. 38-1 (1X)】Cystic mass containing heterogeneous component.

　

 

 

【 Fig. 38-2 (1X)】Dermoid component seen.

　

 

 

【 Fig. 38-3 (4X)】Sebaceous gland, adipose tissue, epithelial component, and cartilage are seen in this view.

　

 

 

【 Fig. 38-4 (10X)】Skin element seen.

　

 

 

【 Fig. 38-5 (10X)】Ciliated epithelium seen in left view.

　

 

　

【 Fig. 38-6 (20X)】Skin element (dermal appendages, e.G. Hair follicles, sebaceous glands) seen in this view.