cell carcinoma & adenomyosis,
A. Brief Descriptions:
95% of squamous cell carcinoma (SCC): keratinizing (well-differentiated) or nonkeratinizing (moderately differentiated) patterns.
<5% of SCC: poorly differentiated small cell wquamous or small cell undifferentiated carcinomas.
The uterine corpus can be directly invaded by SCC of cervix.
B. Gross Findings:
Cancer: fungating (exophytic), ulcerating or infiltrative patterns.
Adenomyosis: irregular fibrotic areas.
C. Micro Findings:
Tumor nests composed of large epidermoid cell infiltrate the myometrium.
Adenomyosis with ectopic islands of endometrial tissue in the myometrium is also present.
Compare with squamous cell carcinoma in situ (slide 83).
Robbins Pathologic Basis of Disease, 6th ed. P.1051-1053.
【 Fig. 173-1 (LP)】Infiltrating tumor nests in the myometrium.
【 Fig. 173-2 (LP)】Anaplastic epidermoid cells arranged in nesty pattern.
【 Fig. 173-3 (LP)】Tumor cells with vesicular nuclei, conspicuous nucleoli and increased mitotic figures.