《Slide 108.》Hyaline membrane disease, Lung

A. Brief Descriptions：

1. A consequence of non-specific injury to the bronchiolar and alveolar lining.

2. Respiratory distress syndrome of new born, always seen in premature infants. (Cause: deficiency of pulmonary surfactiant).

B. Gross Findings：

1. Heavy (because of pulmonary edema ,congestion ), purple and solid appearance of lung.

C. Micro Findings：

1. Pink, fibrin-rich hyaline membranes lining small and collapsed alveolar spaces and necrotic debris mainly within the respiratory bronchioles, alveolar ducts and unopened alveoli.

2. Hyaline membrane: compacted plasma exudates and cellular debris.

D. Others:

   略.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  Ch.11.P.471~473.

　

 

【 Fig. 108-1 (LP)】

　

 

 

【 Fig. 108-2 (LP)】

　

 

 

【 Fig. 108-3 (HP)】