《Slide 108.》Hyaline membrane disease, Lung
A. Brief Descriptions：
A consequence of non-specific injury to the bronchiolar and alveolar lining.
Respiratory distress syndrome of new born, always seen in premature infants. (Cause: deficiency of pulmonary surfactiant).
B. Gross Findings：
Heavy (because of pulmonary edema ,congestion ), purple and solid appearance of lung.
C. Micro Findings：
Pink, fibrin-rich hyaline membranes lining small and collapsed alveolar spaces and necrotic debris mainly within the respiratory bronchioles, alveolar ducts and unopened alveoli.
Hyaline membrane: compacted plasma exudates and cellular debris.
Robbins Pathologic Basis of Disease, 6th ed. Ch.11.P.471~473.
【 Fig. 108-1 (LP)】
【 Fig. 108-2 (LP)】
【 Fig. 108-3 (HP)】