Slide 111.Adenocarcinoma, Lung

A. Brief Descriptions

  1. Usually arise in the periphery of the lung (small bronchus, a bronchiole or the alveoli).

  2. Women appear to have propensity to develop adenocarcinoma.

B. Gross Findings

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C. Micro Findings

  1. Neoplastic cells are generally cuboid to columnar, frequently secrete mucin and form tubular, acinar or papillary structure.

  2. Neoplastic glands with cribriform pattern; note stromal invasion with severe desmplasia.

D. Others:

  1. Most common of primary lung cancer

  2. Most common in female

  3. Location: usually in peripheral, subpleural lung with pleural thickening and puckering

  4. Best prognosis of lung cancer

E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  Ch.16.P.741~746.

 

 

 

Fig. 111-1 (LP)

 

 

 

Fig. 111-2 (LP)

 

 

 

Fig. 111-3 (LP)

 

 

 

Fig. 111-4 (HP)