Slide 111.Adenocarcinoma, Lung

A. Brief Descriptions

  1. Usually arise in the periphery of the lung (small bronchus, a bronchiole or the alveoli).

  2. Women appear to have propensity to develop adenocarcinoma.

B. Gross Findings


C. Micro Findings

  1. Neoplastic cells are generally cuboid to columnar, frequently secrete mucin and form tubular, acinar or papillary structure.

  2. Neoplastic glands with cribriform pattern; note stromal invasion with severe desmplasia.

D. Others:

  1. Most common of primary lung cancer

  2. Most common in female

  3. Location: usually in peripheral, subpleural lung with pleural thickening and puckering

  4. Best prognosis of lung cancer

E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  Ch.16.P.741~746.




Fig. 111-1 (LP)




Fig. 111-2 (LP)




Fig. 111-3 (LP)




Fig. 111-4 (HP)