《Slide 113.》Squamous cell carcinoma, Lung
　

A. Brief Descriptions：

1. Arises in metaplastic squamous epithelium of bronchi.

2. Over 80% of squamous cell carcinomas occur in males and is strongly associated with cigarette smoking.

B. Gross Findings：

1. bulky mass, central or peripheral; central cavitation and necrosis is common.

C. Micro Findings：

1. Range from well-differentiated SCC showing keratin pearls and intercellular bridge to poor- differentiated neoplasm having only minimal residual squamous features and dyskeratocytes.

D. Others:

1. Arises in metaplastic squamous epithelium of bronchi.

2. Accounts for 25-35% of all lung cancers.

3. Over 80% of squamous cell carcinomas occur in males, and is strongly associated with cigarette smoking.

4. Most cases are centered in segmental bronchi.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed. Ch.16. P.741~746.

　

 

 

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