Slide 167.Nonossifying fibroma, Tibia

A. Brief Descriptions

  1. A  benign tumor of bone occurs in adolescents.

  2. Occur almost exclusively in the metaphysis of the long bones, especially the tibia and femur.

B. Gross Findings

  1. Soft, friable, and yellow brown.

  2. Well circumscribed.

C. Micro Findings

  1. Multinuclear giant cells.

  2. Fibrohitiocytic lesion.

  3. Foamy hitiocyte.

  4. Hemorrhage.

D. Others:


E. Reference

  1. Robbins Pathologic Basis of Disease, 6th ed.  P1242.




Fig. 167-1 (LP)Storiform pattern created by benign spindle cells with scattered osteoclast-type giant cells.





Fig. 167-2 (LP) Osteoclast-type giant cells are seen..