《Slide 115.》Actinomycosis, Liver

A. Brief Descriptions：

1. Anaerobic non-spore forming bacteria, gram positive bacilli.

2. Normal commensal organism in the gastrointestinal tract.

3. Sulfar granules : yellowish granules found grossly.

B. Gross Findings：

1. Abscess contain sulfur granules.

C. Micro Findings：

1. Severely destructed liver with abscess formation.

2. In the abscess, sulfur granule with aggregation of Actinomycetic filaments.

D. Others:

1. Compare 《Slide 42.》 Actinomycosis of tongue.

E. Reference：

1. Robbins Pathologic Basis of Disease, 6^th ed.  P.369~370.

　

 

 

【 Fig. 115-1 (LP)】Focal destruction of hepatic parenchymal architecture.

　

 

 

【 Fig. 115-2 (LP)】In abscess area, several dense basophilic sulfur granules are seen.

　

 

 

【 Fig. 115-3 (LP)】Foci of abscess formation showing necrotic debris accumulation with dense neutrophilic infiltration.

　

 

 

【 Fig. 115-4 (HP)】Radial arrangement of Actinomyceles with lymphocytic infiltrate at periphery.